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B Cell Depletion Reduces the Number of Autoreactive T Helper Cells and Prevents Glucose-6-Phosphate Isomerase-Induced Arthritis

The therapeutic benefit of B cell depletion in patients with rheumatoid arthritis has provided proof of concept that B cells are relevant for the pathogenesis of arthritis. It remains unknown which B cell effector functions contribute to the induction or chronification of arthritis. We studied the c...

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Detalhes bibliográficos
Main Authors: Frey, Oliver, Bruns, Lisa, Morawietz, Lars, Dunussi-Joannopoulos, Kyri, Kamradt, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169631/
https://ncbi.nlm.nih.gov/pubmed/21931827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024718
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