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Immunization with an immunodominant self-peptide derived from glucose-6-phosphate isomerase induces arthritis in DBA/1 mice

INTRODUCTION: T-helper (Th) lymphocytes are critically required for the pathogenesis of glucose-6-phosphate isomerase (G6PI)-induced arthritis, but neither the G6PI epitopes recognized by arthritogenic T cells nor their pathogenic effector functions have been fully elucidated to date. We aimed at id...

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Detalhes bibliográficos
Main Authors: Bruns, Lisa, Frey, Oliver, Morawietz, Lars, Landgraf, Christiane, Volkmer, Rudolf, Kamradt, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745800/
https://ncbi.nlm.nih.gov/pubmed/19640302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2777
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