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B1 Cells Promote Pancreas Infiltration by Autoreactive T Cells
The entry of autoreactive T cells into the pancreas is a critical checkpoint in the development of autoimmune diabetes. In this study, we identify a role for B1 cells in this process using the DO11 × RIP-mOVA mouse model. In transgenic mice with islet-specific T cells, but no B cells, T cells are pr...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3983558/ https://ncbi.nlm.nih.gov/pubmed/20675587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000856 |
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