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Toxoplasma gondii Rhoptry Kinase ROP16 Activates STAT3 and STAT6 Resulting in Cytokine Inhibition and Arginase-1-Dependent Growth Control
The ROP16 kinase of Toxoplasma gondii is injected into the host cell cytosol where it activates signal transducer and activator of transcription (STAT)-3 and STAT6. Here, we generated a ROP16 deletion mutant on a Type I parasite strain background, as well as a control complementation mutant with res...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2011
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3169547/ https://ncbi.nlm.nih.gov/pubmed/21931552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002236 |
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