Rhoptry and Dense Granule Secreted Effectors Regulate CD8(+) T Cell Recognition of Toxoplasma gondii Infected Host Cells

Toxoplasma gondii secretes rhoptry (ROP) and dense granule (GRA) effector proteins to evade host immune clearance mediated by interferon gamma (IFN-γ), immunity-related GTPase (IRG) effectors, and CD8(+) T cells. Here, we investigated the role of parasite-secreted effectors in regulating host access...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Rommereim, Leah M., Fox, Barbara A., Butler, Kiah L., Cantillana, Viviana, Taylor, Gregory A., Bzik, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742963/
https://ncbi.nlm.nih.gov/pubmed/31555296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02104
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