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Synaptic Autoregulation by Metalloproteases and γ-Secretase
The proteolytic machinery comprising metalloproteases and γ-secretase, an intramembrane aspartyl protease involved in Alzheimer's disease, cleaves several substrates in addition to the extensively studied amyloid precursor protein. Some of these substrates, such as N-cadherin, are synaptic prot...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3169340/ https://ncbi.nlm.nih.gov/pubmed/21865451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2513-11.2011 |
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