Synaptic Autoregulation by Metalloproteases and γ-Secretase

The proteolytic machinery comprising metalloproteases and γ-secretase, an intramembrane aspartyl protease involved in Alzheimer's disease, cleaves several substrates in addition to the extensively studied amyloid precursor protein. Some of these substrates, such as N-cadherin, are synaptic prot...

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Detalhes bibliográficos
Main Authors: Restituito, Sophie, Khatri, Latika, Ninan, Ipe, Mathews, Paul M., Liu, Xin, Weinberg, Richard J., Ziff, Edward B.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169340/
https://ncbi.nlm.nih.gov/pubmed/21865451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2513-11.2011
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