Wordt geladen...

Allele-specific genetic interactions between Prp8 and RNA active site residues suggest a function for Prp8 at the catalytic core of the spliceosome

The highly conserved spliceosomal protein Prp8 is known to cross-link the critical sequences at both the 5′ (GU) and 3′ (YAG) ends of the intron. We have identified prp8 mutants with the remarkable property of suppressing exon ligation defects due to mutations in position 2 of the 5′ GU, and all pos...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Collins, Catherine A., Guthrie, Christine
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 1999
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC316919/
https://ncbi.nlm.nih.gov/pubmed/10444595
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!