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Human step II splicing factor hSlu7 functions in restructuring the spliceosome between the catalytic steps of splicing

The spliceosome catalyzes pre-mRNA splicing in two steps. After catalytic step I, a major remodeling of the spliceosome occurs to establish the active site for step II. Here, we report the isolation of a cDNA encoding hSlu7, the human homolog of the yeast second step splicing factor Slu7. We show th...

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Udgivet i:Genes Dev
Principais autores: Chua, Katrin, Reed, Robin
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 1999
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316594/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10197984/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.7.841
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