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Multilevel autoregulation of λ repressor protein CI by DNA looping in vitro

The prophage state of bacteriophage λ is extremely stable and is maintained by a highly regulated level of λ repressor protein, CI, which represses lytic functions. CI regulates its own synthesis in a lysogen by activating and repressing its promoter, P(RM). CI participates in long-range interaction...

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Autori principali: Lewis, Dale, Le, Phuoc, Zurla, Chiara, Finzi, Laura, Adhya, Sankar
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169136/
https://ncbi.nlm.nih.gov/pubmed/21873207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111221108
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