The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation
The spindle assembly checkpoint mechanism delays anaphase initiation until all chromosomes are aligned at the metaphase plate. Activation of the anaphase-promoting complex (APC) by binding of CDC20 and CDH1 is required for exit from mitosis, and APC has been implicated as a target for the checkpoint...
I tiakina i:
| I whakaputaina i: | Genes Dev |
|---|---|
| Ngā kaituhi matua: | , , |
| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
Cold Spring Harbor Laboratory Press
1998
|
| Ngā marau: | |
| Urunga tuihono: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316912/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9637688/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.12.1871 |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
|