Structural basis for autorepression of retinoid X receptor by tetramer formation and the AF-2 helix

The 9-cis-retinoic acid receptors (RXRα, RXRβ, and RXRγ) are nuclear receptors that play key roles in multiple hormone-signaling pathways. Biochemical data indicate that, in the absence of ligand, RXR can exist as an inactive tetramer and that its dissociation, induced by ligand, is important for re...

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Dades bibliogràfiques

Publicat a:	Genes Dev
Autors principals:	Gampe, Robert T., Montana, Valerie G., Lambert, Millard H., Wisely, G. Bruce, Milburn, Michael V., Xu, H. Eric
Format:	Artigo
Idioma:	Inglês
Publicat:	Cold Spring Harbor Laboratory Press 2000
Matèries:	Research Paper
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316898/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10970886/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.802300
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