Myc-enhanced expression of Cul1 promotes ubiquitin-dependent proteolysis and cell cycle progression

The c-Myc oncoprotein plays an important role in the growth and proliferation of normal and neoplastic cells. To execute these actions, c-Myc is thought to regulate functionally diverse sets of genes that directly govern cellular mass and progression through critical cell cycle transitions. Here, we...

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Bibliographic Details

Published in:	Genes Dev
Main Authors:	O'Hagan, Rónán C., Ohh, Michael, David, Gregory, de Alboran, Ignacio Moreno, Alt, Frederick W., Kaelin, William G., DePinho, Ronald A.
Format:	Artigo
Language:	Inglês
Published:	Cold Spring Harbor Laboratory Press 2000
Subjects:	Research Paper
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316894/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10970882/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.827200
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