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Myc-enhanced expression of Cul1 promotes ubiquitin-dependent proteolysis and cell cycle progression

The c-Myc oncoprotein plays an important role in the growth and proliferation of normal and neoplastic cells. To execute these actions, c-Myc is thought to regulate functionally diverse sets of genes that directly govern cellular mass and progression through critical cell cycle transitions. Here, we...

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Detalhes bibliográficos
Main Authors: O'Hagan, Rónán C., Ohh, Michael, David, Gregory, de Alboran, Ignacio Moreno, Alt, Frederick W., Kaelin, William G., DePinho, Ronald A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC316894/
https://ncbi.nlm.nih.gov/pubmed/10970882
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