Ventral neural patterning by Nkx homeobox genes: Nkx6.1 controls somatic motor neuron and ventral interneuron fates

There is growing evidence that sonic hedgehog (Shh) signaling regulates ventral neuronal fate in the vertebrate central nervous system through Nkx-class homeodomain proteins. We have examined the patterns of neurogenesis in mice carrying a targeted mutation in Nkx6.1. These mutants show a dorsal-to-...

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Dettagli Bibliografici
Pubblicato in:Genes Dev
Autori principali: Sander, Maike, Paydar, Sussan, Ericson, Johan, Briscoe, James, Berber, Elizabeth, German, Michael, Jessell, Thomas M., Rubenstein, John L.R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2000
Soggetti:
Research Communication
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316892/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10970877/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.820400
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