Ventral neural patterning by Nkx homeobox genes: Nkx6.1 controls somatic motor neuron and ventral interneuron fates

There is growing evidence that sonic hedgehog (Shh) signaling regulates ventral neuronal fate in the vertebrate central nervous system through Nkx-class homeodomain proteins. We have examined the patterns of neurogenesis in mice carrying a targeted mutation in Nkx6.1. These mutants show a dorsal-to-...

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Detalhes bibliográficos
Main Authors: Sander, Maike, Paydar, Sussan, Ericson, Johan, Briscoe, James, Berber, Elizabeth, German, Michael, Jessell, Thomas M., Rubenstein, John L.R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2000
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC316892/
https://ncbi.nlm.nih.gov/pubmed/10970877
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