Degradation of Drosophila PIM regulates sister chromatid separation during mitosis

Drosophila Pimples (PIM) and Three rows (THR) are required for sister chromatid separation in mitosis. PIM accumulates during interphase and is degraded rapidly during mitosis. This degradation is dependent on a destruction box similar to that of B-type cyclins. Nondegradable PIM with a mutant destr...

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Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Leismann, Oliver, Herzig, Alf, Heidmann, Stefan, Lehner, Christian F.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 2000
Assuntos:	Research Paper
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316890/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10970883/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.176700
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