Degradation of Drosophila PIM regulates sister chromatid separation during mitosis

Drosophila Pimples (PIM) and Three rows (THR) are required for sister chromatid separation in mitosis. PIM accumulates during interphase and is degraded rapidly during mitosis. This degradation is dependent on a destruction box similar to that of B-type cyclins. Nondegradable PIM with a mutant destr...

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Pubblicato in:	Genes Dev
Autori principali:	Leismann, Oliver, Herzig, Alf, Heidmann, Stefan, Lehner, Christian F.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cold Spring Harbor Laboratory Press 2000
Soggetti:	Research Paper
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316890/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10970883/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.176700
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