Augmentation of Tonic GABA(A) Inhibition in Absence Epilepsy: Therapeutic Value of Inverse Agonists at Extrasynaptic GABA(A) Receptors

It is well established that impaired GABAergic inhibition within neuronal networks can lead to hypersynchronous firing patterns that are the typical cellular hallmark of convulsive epileptic seizures. However, recent findings have highlighted that a pathological enhancement of GABAergic signalling w...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Errington, Adam C., Cope, David W., Crunelli, Vincenzo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Hindawi Publishing Corporation 2011
Gaiak:
Review Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3168769/
https://ncbi.nlm.nih.gov/pubmed/21912539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/790590
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