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γ-Hydroxybutyric Acid (GHB) Is Not an Agonist of Extrasynaptic GABA(A) Receptors

γ-Hydroxybutyric acid (GHB) is an endogenous compound and a drug used clinically to treat the symptoms of narcolepsy. GHB is known to be an agonist of GABA(B) receptors with millimolar affinity, but also binds with much higher affinity to another site, known as the GHB receptor. While a body of evid...

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書目詳細資料
Main Authors: Connelly, William M., Errington, Adam C., Crunelli, Vincenzo
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823990/
https://ncbi.nlm.nih.gov/pubmed/24244421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079062
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