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Enhanced tonic GABA(A) inhibition in typical absence epilepsy

The cellular mechanisms underlying typical absence seizures, which characterize various idiopathic generalized epilepsies, are not fully understood, but impaired GABAergic inhibition remains an attractive hypothesis. In contrast, we show here that extrasynaptic GABA(A) receptor–dependent ‘tonic’ inh...

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Dettagli Bibliografici
Autori principali: Cope, David W., Di Giovanni, Giuseppe, Fyson, Sarah J., Orbán, Gergely, Errington, Adam C., Lőrincz, Magor L., Gould, Timothy M., Carter, David A., Crunelli, Vincenzo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824149/
https://ncbi.nlm.nih.gov/pubmed/19966779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2058
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