Enhanced tonic GABA(A) inhibition in typical absence epilepsy

The cellular mechanisms underlying typical absence seizures, which characterize various idiopathic generalized epilepsies, are not fully understood, but impaired GABAergic inhibition remains an attractive hypothesis. In contrast, we show here that extrasynaptic GABA(A) receptor–dependent ‘tonic’ inh...

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Detalhes bibliográficos
Main Authors: Cope, David W., Di Giovanni, Giuseppe, Fyson, Sarah J., Orbán, Gergely, Errington, Adam C., Lőrincz, Magor L., Gould, Timothy M., Carter, David A., Crunelli, Vincenzo
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824149/
https://ncbi.nlm.nih.gov/pubmed/19966779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2058
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