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A new direction for anticoagulants: Inhibiting fibrin assembly with PEGylated fibrin knob mimics
Current anticoagulants target coagulation Factors upstream from fibrin assembly and polymerization (i.e. formation of fibrin clot). While effective, this approach requires constant patient monitoring since pharmacokinetics and pharmacodynamics vary from patient to patient. To address these limitatio...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3168719/ https://ncbi.nlm.nih.gov/pubmed/21520023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.23184 |
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