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The surveillance complex interacts with the translation release factors to enhance termination and degrade aberrant mRNAs

The nonsense-mediated mRNA decay pathway is an example of an evolutionarily conserved surveillance pathway that rids the cell of transcripts that contain nonsense mutations. The product of the UPF1 gene is a necessary component of the putative surveillance complex that recognizes and degrades aberra...

詳細記述

保存先:
書誌詳細
主要な著者: Czaplinski, Kevin, Ruiz-Echevarria, Maria J., Paushkin, Sergey V., Han, Xia, Weng, Youmin, Perlick, Haley A., Dietz, Harry C., Ter-Avanesyan, Michael D., Peltz, Stuart W.
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC316864/
https://ncbi.nlm.nih.gov/pubmed/9620853
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