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The surveillance complex interacts with the translation release factors to enhance termination and degrade aberrant mRNAs
The nonsense-mediated mRNA decay pathway is an example of an evolutionarily conserved surveillance pathway that rids the cell of transcripts that contain nonsense mutations. The product of the UPF1 gene is a necessary component of the putative surveillance complex that recognizes and degrades aberra...
Sparad:
| I publikationen: | Genes Dev |
|---|---|
| Huvudupphovsmän: | , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Cold Spring Harbor Laboratory Press
1998
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316864/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9620853/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.11.1665 |
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