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Identifying the right stop: determining how the surveillance complex recognizes and degrades an aberrant mRNA.
The nonsense-mediated mRNA decay (NMD) pathway functions by checking whether translation termination has occurred prematurely and subsequently degrading the aberrant mRNAs. In Saccharomyces cerevisiae, it has been proposed that a surveillance complex scans 3' of the premature termination codon...
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| Hoofdauteurs: | , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
1998
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170407/ https://ncbi.nlm.nih.gov/pubmed/9430648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.2.575 |
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