tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c

TNFR1/Fas engagement results in the cleavage of cytosolic BID to truncated tBID, which translocates to mitochondria. Immunodepletion and gene disruption indicate BID is required for cytochrome c release. Surprisingly, the three-dimensional structure of this BH3 domain-only molecule revealed two hydr...

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Dades bibliogràfiques

Publicat a:	Genes Dev
Autors principals:	Wei, Michael C., Lindsten, Tullia, Mootha, Vamsi K., Weiler, Solly, Gross, Atan, Ashiya, Mona, Thompson, Craig B., Korsmeyer, Stanley J.
Format:	Artigo
Idioma:	Inglês
Publicat:	Cold Spring Harbor Laboratory Press 2000
Matèries:	Research Paper
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316859/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10950869/
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