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Defective processing of methylated single-stranded DNA by E. coli alkB mutants

Escherichia coli alkB mutants are very sensitive to DNA methylating agents. Despite these mutants being the subject of many studies, no DNA repair or other function has been assigned to the AlkB protein or to its human homolog. Here, we report that reactivation of methylmethanesulfonate (MMS)-treate...

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Detalhes bibliográficos
Publicado no:Genes Dev
Principais autores: Dinglay, Suneet, Trewick, Sarah C., Lindahl, Tomas, Sedgwick, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316854/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10950872/
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