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Defective processing of methylated single-stranded DNA by E. coli alkB mutants

Escherichia coli alkB mutants are very sensitive to DNA methylating agents. Despite these mutants being the subject of many studies, no DNA repair or other function has been assigned to the AlkB protein or to its human homolog. Here, we report that reactivation of methylmethanesulfonate (MMS)-treate...

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Autores principales: Dinglay, Suneet, Trewick, Sarah C., Lindahl, Tomas, Sedgwick, Barbara
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC316854/
https://ncbi.nlm.nih.gov/pubmed/10950872
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