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The Escherichia coli AlkB protein protects human cells against alkylation-induced toxicity.

Escherichia coli can ameliorate the toxic effects of alkylating agents either by preventing DNA alkylation or by repairing DNA alkylation damage. The alkylation-sensitive phenotype of E. coli alkB mutants marks the alkB pathway as an extremely effective defense mechanism against the cytotoxic effect...

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Sonraí Bibleagrafaíochta
Main Authors: Chen, B J, Carroll, P, Samson, L
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1994
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC196966/
https://ncbi.nlm.nih.gov/pubmed/7928996
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