The Escherichia coli AlkB protein protects human cells against alkylation-induced toxicity.
Escherichia coli can ameliorate the toxic effects of alkylating agents either by preventing DNA alkylation or by repairing DNA alkylation damage. The alkylation-sensitive phenotype of E. coli alkB mutants marks the alkB pathway as an extremely effective defense mechanism against the cytotoxic effect...
Guardat en:
| Publicat a: | J Bacteriol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1994
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196966/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7928996/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.20.6255-6261.1994 |
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