The Escherichia coli AlkB protein protects human cells against alkylation-induced toxicity.

Escherichia coli can ameliorate the toxic effects of alkylating agents either by preventing DNA alkylation or by repairing DNA alkylation damage. The alkylation-sensitive phenotype of E. coli alkB mutants marks the alkB pathway as an extremely effective defense mechanism against the cytotoxic effect...

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Библиографические подробности

Опубликовано в::	J Bacteriol
Главные авторы:	Chen, B J, Carroll, P, Samson, L
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 1994
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196966/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7928996/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.20.6255-6261.1994
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