A transcriptional insulator at the imprinted H19/Igf2 locus

Igf2 and H19 exhibit parent-of-origin-specific monoallelic expression. H19 is expressed from the maternal chromosome and Igf2 from the paternal. The two genes share enhancer elements and monoallelic expression of both genes is dependent on cis-acting sequences upstream of the H19 promoter. In this w...

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Main Authors: Kaffer, Christopher R., Srivastava, Madhulika, Park, Kye-Yoon, Ives, Elizabeth, Hsieh, Sandra, Batlle, Juan, Grinberg, Alexander, Huang, Sing-Ping, Pfeifer, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2000
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC316810/
https://ncbi.nlm.nih.gov/pubmed/10921905
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