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Cdc53/cullin and the essential Hrt1 RING–H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34

SCF(Cdc4) (Skp1, Cdc53/cullin, F-box protein) defines a family of modular ubiquitin ligases (E3s) that regulate diverse processes including cell cycle, immune response, and development. Mass spectrometric analysis of proteins copurifying with Cdc53 identified the RING–H2 finger protein Hrt1 as a sub...

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Publicado no:Genes Dev
Principais autores: Seol, Jae Hong, Feldman, R.M. Renny, Zachariae, Wolfgang, Shevchenko, Anna, Correll, Craig C., Lyapina, Svetlana, Chi, Yong, Galova, Marta, Claypool, Jonathan, Sandmeyer, Suzanne, Nasmyth, Kim, Shevchenko, Andrej, Deshaies, Raymond J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1999
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316801/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10385629/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.12.1614
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