Roles of DNA polymerase I in leading and lagging-strand replication defined by a high-resolution mutation footprint of ColE1 plasmid replication

DNA polymerase I (pol I) processes RNA primers during lagging-strand synthesis and fills small gaps during DNA repair reactions. However, it is unclear how pol I and pol III work together during replication and repair or how extensive pol I processing of Okazaki fragments is in vivo. Here, we addres...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Allen, Jennifer M., Simcha, David M., Ericson, Nolan G., Alexander, David L., Marquette, Jacob T., Van Biber, Benjamin P., Troll, Chris J., Karchin, Rachel, Bielas, Jason H., Loeb, Lawrence A., Camps, Manel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
Soggetti:
Genome Integrity, Repair and Replication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167613/
https://ncbi.nlm.nih.gov/pubmed/21622658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr157
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi