Quadruplex formation is necessary for stable PNA invasion into duplex DNA of BCL2 promoter region

Guanine-rich sequences are highly abundant in the human genome, especially in regulatory regions. Because guanine-rich sequences have the unique ability to form G-quadruplexes, these structures may play a role in the regulation of gene transcription. In previous studies, we demonstrated that formati...

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Bibliografiske detaljer
Main Authors: Onyshchenko, Mykola I., Gaynutdinov, Timur I., Englund, Ethan A., Appella, Daniel H., Neumann, Ronald D., Panyutin, Igor G.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Molecular Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167611/
https://ncbi.nlm.nih.gov/pubmed/21593130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr259
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