G-Quadruplex Formation Between G-Rich PNA and Homologous Sequences in Oligonucleotides and Supercoiled Plasmid DNA

Guanine (G)-rich DNA sequences can adopt four-stranded quadruplex conformations that may play a role in the regulation of genetic processes. To explore the possibility of targeted molecular recognition of DNA sequences with short G-rich peptide nucleic acids (PNA) and to assess the strand arrangemen...

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Bibliografske podrobnosti
izdano v:Nucleic Acid Ther
Main Authors: Gaynutdinov, Timur I., Englund, Ethan A., Appella, Daniel H., Onyshchenko, Mykola I., Neumann, Ronald D., Panyutin, Igor G.
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2015
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376483/
https://ncbi.nlm.nih.gov/pubmed/25650982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2014.0517
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