BlastR—fast and accurate database searches for non-coding RNAs

We present and validate BlastR, a method for efficiently and accurately searching non-coding RNAs. Our approach relies on the comparison of di-nucleotides using BlosumR, a new log-odd substitution matrix. In order to use BlosumR for comparison, we recoded RNA sequences into protein-like sequences. W...

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Bibliografske podrobnosti
Main Authors: Bussotti, Giovanni, Raineri, Emanuele, Erb, Ionas, Zytnicki, Matthias, Wilm, Andreas, Beaudoing, Emmanuel, Bucher, Philipp, Notredame, Cedric
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2011
Teme:
Computational Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167602/
https://ncbi.nlm.nih.gov/pubmed/21624887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr335
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