Cryptococcus neoformans mating and virulence are regulated by the G-protein α subunit GPA1 and cAMP

This study explores signal transduction pathways that function during mating and infection in the opportunistic, human fungal pathogen Cryptococcus neoformans. The gene encoding a G-protein α subunit homolog, GPA1, was disrupted by homologous recombination. The gpa1 mutant strain was viable but exhi...

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Bibliografiske detaljer
Main Authors: Alspaugh, J. Andrew, Perfect, John R., Heitman, Joseph
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 1997
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC316752/
https://ncbi.nlm.nih.gov/pubmed/9389652
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