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Cryptococcus neoformans mating and virulence are regulated by the G-protein α subunit GPA1 and cAMP

This study explores signal transduction pathways that function during mating and infection in the opportunistic, human fungal pathogen Cryptococcus neoformans. The gene encoding a G-protein α subunit homolog, GPA1, was disrupted by homologous recombination. The gpa1 mutant strain was viable but exhi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Genes Dev
Hauptverfasser: Alspaugh, J. Andrew, Perfect, John R., Heitman, Joseph
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 1997
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316752/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9389652/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.11.23.3206
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