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Critical assessment of nucleic acid electrostatics via experimental and computational investigation of an unfolded state ensemble

Electrostatic forces, acting between helices and modulated by the presence of the ion atmosphere, are key determinants in the energetic balance that governs RNA folding. Previous studies have employed Poisson-Boltzmann (PB) theory to compute the energetic contribution of these forces in RNA folding....

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Detalhes bibliográficos
Main Authors: Bai, Yu, Chu, Vincent B., Lipfert, Jan, Pande, Vijay S., Herschlag, Daniel, Doniach, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167486/
https://ncbi.nlm.nih.gov/pubmed/18722445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja800854u
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