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Do conformational biases of simple helical junctions influence RNA folding stability and specificity?

Structured RNAs must fold into their native structures and discriminate against a large number of alternative ones, an especially difficult task given the limited information content of RNA's nucleotide alphabet. The simplest motifs within structured RNAs are two helices joined by nonhelical ju...

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Detalhes bibliográficos
Main Authors: Chu, Vincent B., Lipfert, Jan, Bai, Yu, Pande, Vijay S., Doniach, Sebastian, Herschlag, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779674/
https://ncbi.nlm.nih.gov/pubmed/19850914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1747509
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