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Do conformational biases of simple helical junctions influence RNA folding stability and specificity?
Structured RNAs must fold into their native structures and discriminate against a large number of alternative ones, an especially difficult task given the limited information content of RNA's nucleotide alphabet. The simplest motifs within structured RNAs are two helices joined by nonhelical ju...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2779674/ https://ncbi.nlm.nih.gov/pubmed/19850914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1747509 |
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