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Do conformational biases of simple helical junctions influence RNA folding stability and specificity?

Structured RNAs must fold into their native structures and discriminate against a large number of alternative ones, an especially difficult task given the limited information content of RNA's nucleotide alphabet. The simplest motifs within structured RNAs are two helices joined by nonhelical ju...

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Autors principals: Chu, Vincent B., Lipfert, Jan, Bai, Yu, Pande, Vijay S., Doniach, Sebastian, Herschlag, Daniel
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779674/
https://ncbi.nlm.nih.gov/pubmed/19850914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1747509
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