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Do conformational biases of simple helical junctions influence RNA folding stability and specificity?

Structured RNAs must fold into their native structures and discriminate against a large number of alternative ones, an especially difficult task given the limited information content of RNA's nucleotide alphabet. The simplest motifs within structured RNAs are two helices joined by nonhelical ju...

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Hlavní autoři: Chu, Vincent B., Lipfert, Jan, Bai, Yu, Pande, Vijay S., Doniach, Sebastian, Herschlag, Daniel
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779674/
https://ncbi.nlm.nih.gov/pubmed/19850914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1747509
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