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Do conformational biases of simple helical junctions influence RNA folding stability and specificity?

Structured RNAs must fold into their native structures and discriminate against a large number of alternative ones, an especially difficult task given the limited information content of RNA's nucleotide alphabet. The simplest motifs within structured RNAs are two helices joined by nonhelical ju...

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Détails bibliographiques
Auteurs principaux: Chu, Vincent B., Lipfert, Jan, Bai, Yu, Pande, Vijay S., Doniach, Sebastian, Herschlag, Daniel
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779674/
https://ncbi.nlm.nih.gov/pubmed/19850914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1747509
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