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Transforming binding affinities from 3D to 2D with application to cadherin clustering

Membrane-bound receptors often form large assemblies resulting from binding to soluble ligands, cell-surface molecules on other cells, and extracellular matrix proteins(1). For example, the association of membrane proteins with proteins on different cells (trans interactions) can drive the oligomeri...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wu, Yinghao, Vendome, Jeremie, Shapiro, Lawrence, Ben-Shaul, Avinoam, Honig, Barry
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167384/
https://ncbi.nlm.nih.gov/pubmed/21796210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10183
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