K(Ca)3.1 channels facilitate K(+) secretion or Na(+) absorption depending on apical or basolateral P2Y receptor stimulation

ABSTRACT: Human mammary epithelial (HME) cells express several P2Y receptor subtypes located in both apical and basolateral membranes. Apical UTP or ATP-γ-S stimulation of monolayers mounted in Ussing chambers evoked a rapid, but transient decrease in short circuit current (I(sc)), consistent with a...

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Autores principales: Palmer, Melissa L, Peitzman, Elizabeth R, Maniak, Peter J, Sieck, Gary C, Prakash, Y S, O'Grady, Scott M
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2011
Materias:
Molecular and Cellular
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167112/
https://ncbi.nlm.nih.gov/pubmed/21606112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.207548
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