Post-transcriptional generation of miRNA variants by multiple nucleotidyl transferases contributes to miRNA transcriptome complexity

Modification of microRNA sequences by the 3′ addition of nucleotides to generate so-called “isomiRs” adds to the complexity of miRNA function, with recent reports showing that 3′ modifications can influence miRNA stability and efficiency of target repression. Here, we show that the 3′ modification o...

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Detalhes bibliográficos
Main Authors: Wyman, Stacia K., Knouf, Emily C., Parkin, Rachael K., Fritz, Brian R., Lin, Daniel W., Dennis, Lucas M., Krouse, Michael A., Webster, Philippa J., Tewari, Muneesh
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166830/
https://ncbi.nlm.nih.gov/pubmed/21813625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.118059.110
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