Post-transcriptional generation of miRNA variants by multiple nucleotidyl transferases contributes to miRNA transcriptome complexity

Modification of microRNA sequences by the 3′ addition of nucleotides to generate so-called “isomiRs” adds to the complexity of miRNA function, with recent reports showing that 3′ modifications can influence miRNA stability and efficiency of target repression. Here, we show that the 3′ modification o...

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Autors principals: Wyman, Stacia K., Knouf, Emily C., Parkin, Rachael K., Fritz, Brian R., Lin, Daniel W., Dennis, Lucas M., Krouse, Michael A., Webster, Philippa J., Tewari, Muneesh
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2011
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166830/
https://ncbi.nlm.nih.gov/pubmed/21813625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.118059.110
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