Post-transcriptional generation of miRNA variants by multiple nucleotidyl transferases contributes to miRNA transcriptome complexity

Modification of microRNA sequences by the 3′ addition of nucleotides to generate so-called “isomiRs” adds to the complexity of miRNA function, with recent reports showing that 3′ modifications can influence miRNA stability and efficiency of target repression. Here, we show that the 3′ modification o...

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Bibliografske podrobnosti
Main Authors: Wyman, Stacia K., Knouf, Emily C., Parkin, Rachael K., Fritz, Brian R., Lin, Daniel W., Dennis, Lucas M., Krouse, Michael A., Webster, Philippa J., Tewari, Muneesh
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2011
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166830/
https://ncbi.nlm.nih.gov/pubmed/21813625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.118059.110
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