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Characterization of a Transgenic Short Hairpin RNA-Induced Murine Model of Tafazzin Deficiency
Barth's syndrome (BTHS) is an X-linked mitochondrial disease that is due to a mutation in the Tafazzin (TAZ) gene. Based on sequence homology, TAZ has been characterized as an acyltransferase involved in the metabolism of cardiolipin (CL), a unique phospholipid almost exclusively located in the...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3166794/ https://ncbi.nlm.nih.gov/pubmed/21091282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2010.199 |
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