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Characterization of a Transgenic Short Hairpin RNA-Induced Murine Model of Tafazzin Deficiency

Barth's syndrome (BTHS) is an X-linked mitochondrial disease that is due to a mutation in the Tafazzin (TAZ) gene. Based on sequence homology, TAZ has been characterized as an acyltransferase involved in the metabolism of cardiolipin (CL), a unique phospholipid almost exclusively located in the...

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Bibliografiska uppgifter
Huvudupphovsmän: Soustek, Meghan S., Falk, Darin J., Mah, Cathryn S., Toth, Matthew J., Schlame, Michael, Lewin, Alfred S., Byrne, Barry J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Mary Ann Liebert, Inc. 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166794/
https://ncbi.nlm.nih.gov/pubmed/21091282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2010.199
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