EGF domain swap converts a Drosophila EGF receptor activator into an inhibitor

In Drosophila the function of the epidermal growth factor (EGF) receptor is modulated zygotically by three EGF-like proteins: Spitz (Spi), which is a potent activator; Vein (Vn), which is a moderate activator; and Argos (Aos), which is an inhibitor. Chimeric molecules were constructed in which the E...

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Détails bibliographiques

Publié dans:	Genes Dev
Auteurs principaux:	Schnepp, Bruce, Donaldson, Timothy, Grumbling, Gary, Ostrowski, Stephen, Schweitzer, Ronen, Shilo, Ben-Zion, Simcox, Amanda
Format:	Artigo
Langue:	Inglês
Publié:	Cold Spring Harbor Laboratory Press 1998
Sujets:	Research Communication
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316677/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9531530/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.7.908
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