A splice variant of CD44 expressed in the apical ectodermal ridge presents fibroblast growth factors to limb mesenchyme and is required for limb outgrowth

Signals from the apical ectodermal ridge (AER) of the developing vertebrate limb, including fibroblast growth factor-8 (FGF-8), can maintain limb mesenchymal cells in a proliferative state. We report here that a specific CD44 splice variant is crucial for the proliferation of these mesenchymal cells...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	Genes Dev
Principais autores:	Sherman, Larry, Wainwright, David, Ponta, Helmut, Herrlich, Peter
Format:	Artigo
Sprog:	Inglês
Udgivet:	Cold Spring Harbor Laboratory Press 1998
Fag:	Research Paper
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316674/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9531542/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.7.1058
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!